absolutely cant cum!

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I'm on medication right now and this is making it absolutely impossible to cum.
I can jack off for hours and nothing happens! Then only way to cum is when I put a finger
up my ass when jacking off. How crazy is this?
I also bought an anal vibrator but I'm too worried to use it. I worry about contamination. It's made
of silicone. I don't know if I can use alcohol on it. I could use a condom but I don't know if I'm allergic
to them or to the lube. This sucks.

@stuw Welcome to A2A. It is true that some medications do hold you back, and it can be frustrating. I don't know what medication you are speaking of, but could you discuss the problem with your doctor and see if there is an alternate medication that does not cause these side effects?

Silicone is usually not bothered by alcohol, so you should be safe. As far as allergies go, latex is usually more of a problem than polyurethane. If you have access to latex, you might try rubbing it on your inner arm and see if it causes you any problems.

I'm taking something called amitryptiline. It's supposed to help with my lower back and neck pain.
But this shit has tons of possible side effects it's pretty crazy. The side effects which I notice are harder stools, really stinky farts and the orgasm issues. I even bought a tenga plastic pussy. I thought if I cannot cum when I use my hands then it must definitely work when I use a plastic pussy but today I tried it and I could bang this thing for over an hour without even getting close to cumming! I bet this drug is fantastic if you want to be able to bang chicks for hours without cumming but to me it's very frustrating. The ONLY way now for me to cum is to jack off while at the same time fingering my ass!
That's not normal!

Hi stuw, this difficulty in reaching orgasm is very common with amitryptiline (and most other serotonin reuptake inhibitors). It is unfortunately a common treatment for neuropathic pain, and even more unfortunately most of the alternative medications have the same effect, though there are a few that don't. Bupropion has been reported to be effective for neuropathic pain (see http://en.wikipedia.org/wiki/Neuropathic_pain ) and doesn't have this side-effect, so you might talk to your doctor about it

I tried wellbutrin already. Didn't really do much.
I don't understand why antidepressants are supposed to help with pain.
Maybe the companies simply want to make more money and claim that they
also help with pain. It really sucks. I doubt that there are any drugs which I could take
to fight this side effect which wouldn't interact with amitryptiline.

@stuw said:

I don't understand why antidepressants are supposed to help with pain.

I don't think anyone understands that yet. (For that matter, we don't really understand how antidepressants help with depression.) It's real--drug companies can't make up uses for their drugs: to be an on-label use they have to convince the appropriate authority with proper studies that the drug works significantly better than placebo. However, they don't work with every sort of pain.

If the amitryptiline is helping with the pain, then the side-effects might be worth it. If you don't feel the side-effects are worth the amount of pain reduction, that article I quoted does suggest some other possibilities (not all of which may be desirable treatments for other reasons).

If you are finding the amitryptiline is not helping with the pain much, it's possible the pain may not have a neuropathic cause and needs other treatments.

Do you know if all tricyclic antidepressants have the same sexual side effects?
Aren't there antidepressants which help against pain and also make you horny?
Wellbutrin was said to increase libido but for me it didn't. But at least I could still cum.

Conventional antidepressants work by increasing the levels of one or more of three neurotransmitters: serotonin, norepinephrine and dopamine. Amitriptyline, for example, increases serotonin most, then norepinephrine; dopamine hardly at all. Bupropion increases dopamine level most, then norepinephrine; serotonin hardly at all. The sexual side-effects are associated with increase in serotonin, which is why bupropion doesn't have them. Serotonin seems however to also be associated with anti-anxiety effects, so the serotonin antidepressants are best for also relieving anxiety. For chronic/neuropathic pain it seems that norepinephrine might be important, but possibly also serotonin. The antidepressants most often used for chronic pain are ones that affect both serotonin and norepinephrine: as well as amitriptyline, venlafaxine, duloxetine and milnacipran are used--these are not tricyclics but they have the same effect.

Amineptine is a tricyclic antidepressant that doesn't make it hard to achieve orgasm, because it only works on dopamine. But the chances are it won't do anything for pain (and it has been withdrawn from the market in many places due to abuse potential).

Mirtazepine is an antidepressant that increases both norepinephrine and serotonin, but it blocks the specific receptors responsible for the sexual side-effects. However it doesn't seem to be used for pain: I don't know if that means it hasn't been tried, or has been tried and found ineffective. However trazodone, which only affects serotonin but also blocks the 'bad' specific receptors, has been used for pain, and might be worth trying. It also helps with anxiety and insomnia, and has even been used for treating erectile dysfunction.

Amineptine isn't on the market anymore. It's sad cause I'd like to have tried it. It sounded really good.
I'm not sure how likely it is that if amitryptiline doesn't work that another antidepressant which
also works on norepinephrine should work. Isn't this illogical?
And the whole stuff about serotonin helping against anxiety is also not true. I'm not buying that.
I am no less anxious than before I went on this drug. It seems to be doing something cause I
can't cum anymore but other than that it doesn't seem to be doing anything positive.

I forgot to mention desipramine, which is a tricyclic with reduced serotonin effect (it works mainly through norepinephrine, which is rare), so it should be better--but it doesn't seem very good for pain.

I have found some papers that claim mirtazepine is effective for pain: a few small studies on rat models, one on humans, and a few anecdotal papers like this one.

It really isn't clear what neurotransmitters are useful for pain relief. Most of the agents used affect both serotonin and norepinephrine levels, but bupropion doesn't touch serotonin levels, while trazodone doesn't touch norepinephrin levels (but you found bupropion ineffective, and some have reported trazodone to be ineffective).

There are some reviews published in 2008, 2012 and 2013.

The dose levels used for pain are usually lower than those used for depression or anxiety.

Hi,
I think I will have to get of amitryptiline. It makes my heart beat really fast even without any exercise.
I am also sick of the dry mouth all the time. Maybe I could try duloxetine.