Some reason i've been wondering can any kind of STD change your DNA and the way you look?. Just a question that i just started to think about..
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Can this happen?
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Some STDs, like herpes, change the DNA in a few of your cells, but they don't make you look different (except their usual effects).
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STDs can change the way you look through stress and ,for the more serious diseases, health. In my knowledge, DNA change doesn't occur to any large scale.